This sensory network governs the migration of bacteria towards chemical attractants and away from repellents by translating temporal changes in the level of chemical stimuli into a modulation of the cell’s swimming direction. This is achieved bycontrolling the frequency of abrupt direction changes called tumbles. An important feature of chemotaxis is exact adaptation: achange in the concentration of a chemical stimulant induces a rapid change in the bacteria’s tumbling frequency, which gradually adapts back precisely to its pre stimulus value7,8.Once the components of a biochemical network are isolated and their interactions characterized, the mechanisms of the network’s functioning can be addressed.
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